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Breast density linked to risk for invasive breast cancer in of us over 65

Breast density linked to risk for invasive breast cancer in ≥65s

(HealthDay)—For girls folk susceptible 65 years or older, breast density is expounded to an elevated risk for invasive breast cancer, in step with a compare published on-line Aug. 26 in JAMA Network Start.

Shailesh M. Advani, M.D., Ph.D., from Georgetown University in Washington, D.C., and colleagues conducted a prospective cohort compare intriguing U.S. girls folk susceptible 65 years or older who underwent screening mammography. The 5-year cumulative incidence of invasive breast cancer became as soon as calculated by level of breast density and age.

Recordsdata had been included for 221,714 screening mammograms from 193,787 girls folk; 38 p.c had been susceptible 75 years or older. The researchers chanced on that among girls folk susceptible 65 to 74 years and among those susceptible 75 years or older, the 5-year cumulative incidence of invasive breast cancer elevated in association with rising breast density. In each and all ages classes, crude or heterogeneous breast density became as soon as linked to an elevated risk for breast cancer in contrast with scattered fibroglandular breast density (hazard ratios, 1.39 and 1.23 for those susceptible 65 to 74 and ≥75 years, respectively). When in contrast with girls folk with scattered fibroglandular breast density, those with virtually entirely fatty breasts had a reduced risk for invasive breast cancer (hazard ratios, 0.66 and 0.73, respectively).

“The sure associations display cowl on this compare between breast density and breast cancer among girls folk susceptible 75 years or older counsel that breast density and life expectancy must be regarded as collectively when discussing the doable benefits and harms of continued screening mammography on this inhabitants,” the authors write.



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retrieved 26 August 2021
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