Science and Nature

Proteomics

US 10,989,716 Strategies of diagnosing acute rejection of a cardiac allograft in a subject using genomic expression profiling, proteomic expression profiling, or both on panels of nucleic acid markers and proteomic markers. The University of British Columbia (Vancouver, BC, Canada) McManus B, Ng R, Tebbutt S, Wilson-McManus J, Hollander Z, Lam Okay, Chen V, Dai D, Shannon C, Ignaszewski A, Balshaw R, McMaster R, Keown P 4/27/2021 US 10,948,497 A proteomic expression platform to establish age-linked sepsis menace. A semiquantitative plasma proteomics workflow used to be utilized that incorporated tandem immunoaffinity depletion, iTRAQ labeling, strong cation trade fractionation, and nanoflow liquid chromatography coupled to high resolution mass spectrometry to determine on a protein profile that shows statistically important differences in expression ranges amongst sufferers with severe sepsis as a characteristic of age. The University of Pittsburgh (Pittsburgh, PA, USA) Kellum JA, Cao Z, Angus D, Yende SP, Robinson RAS 3/16/2021 US 10,900,977 Strategies of figuring out whether a subject has an elevated menace of tormented by memory impairment, comprising examining no lower than one plasma sample from the subject to determine on a label of the subject’s proteomic profile and evaluating the price of the subject’s proteomic profile with the price of a fashioned proteomic profile. A distinction in the price of the subject’s proteomic profile from fashioned values means that the subject has an elevated menace of tormented by memory impairment in contrast to a particular person with fashioned values. Georgetown University (Washington, DC, USA), University of Rochester (Rochester, NY, USA) Federoff HJ, Fiandaca MS, Cheema AK, Mapstone ME, Zhong X 1/26/2021 US 10,895,574 Strategies and presents for spend in scientific and research capabilities directed to cancers. Merchandise embody binding arrays; to illustrate, hybridization or other hiss binding arrays a lot like genomic or proteomic microarrays. University of South Carolina (Columbia, SC, USA) Ramsdell AF 1/19/2021 US 10,725,040 A proteomic manner for identification of hiss bacterial protein profiles that will almost definitely be old in the advance of suggestions for the diagnosis of bacterial chronic sinusitis. The invention presents for suggestions of figuring out the presence of pathogenic micro organism in the easier respiratory tract of a subject using protein profiles of the pathogenic micro organism. Furthermore, suggestions of diagnosing a bacterial an infection of the easier respiratory tract of a subject using protein profiles of a pathogenic bacterium. As nicely as, the invention presents for devices, immunoassays and kits for identifying pathogenic micro organism in the easier respiratory tract. Nationwide Younger of us’s Clinic (Columbus, OH, USA), The Ohio Philosophize University (Columbus, OH, USA) Das S, Bakaletz LO 7/28/2020 US 10,671,632 An computerized pipeline that receives a list of accession codes equivalent to transcriptomic, proteomic, genomic or metabolomic data. The accession codes are submitted in parallel, launching a hiss cloud computer to realize a customized, absolutely computerized transcriptome assembly (or proteome assembly or genome assembly or metabolome assembly) and diagnosis by the computerized pipeline. CB Therapeutics (Carlsbad, CA, USA) Yacoub TJ 6/2/2020 US 10,497,466 Systems and suggestions for calculating protein self belief values. A protein database is hunted for proteins matching peptides realized from mass spectrometry of a sample producing a enviornment of proteins and a corresponding enviornment of peptides. Peptide self belief values for the enviornment of peptides are particular. Protein self belief values are calculated for the enviornment of proteins on the premise of the peptide self belief values. Protein self belief values are recalculated for the enviornment of proteins on the premise of the peptide self belief values and an set of taking away the one or extra peptides from the enviornment of peptides. DH Applied sciences Construction Pte. Ltd. (Singapore) Shilov IV 12/3/2019

Related Articles

Back to top button
%d bloggers like this: