Science and Nature

Swarming motility in host defense


Swarming is a collective circulation that has some distance-reaching implications in biology and beyond. Swarms involve teams of individuals coordinating their habits in a self-organizing route of. Examples consist of swarming motility and quorum sensing in bacteria (1), foraging in ants, and the defensive actions of honey bees. In the animal immune machine, swarms of white blood cells called neutrophils acknowledge to microbial threats and tissue hurt by touring en masse to affected tissues. Even though powerful work has been done to designate the initiation of neutrophil swarms (2), less is identified about how they’re terminated. On page 1303 of this plight, Kienle et al. (3) recount that neutrophils limit their swarms by deactivating their gather receptors that detect self-produced swarm alerts. This desensitization limits neutrophil aggregation and, crucially, promotes pathogen clearance and decision of acute inflammatory responses.

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