In fact one of basically the most enduring themes in human neuroscience is the association of higher mind capabilities with gray topic. In direct, the cerebral cortex—the grey topic of the mind’s ground—has been the most predominant focal level of a few years of labor aiming to price the neurobiological foundation of cognition and emotion. Yet, the cerebral cortex is simplest a pair of millimeters thick, so the relative neglect of the the leisure of the mind below the cortex has precipitated the time period “corticocentric myopia” (1). Other areas linked to behavior embody the deep gray topic of the basal ganglia and thalamus, the brainstem and cerebellum, and the white topic that interconnects all of these structures. On page 1304 of this field, Zhao et al. (2) display conceal compelling proof for the significance of white topic by demonstrating genetic influences on structural connectivity that invoke a host of inviting scientific implications.